Targeting epigenetic mechanisms for pain relief
Highlights ► Epigenetic mechanisms are engaged after injury and in chronic pain states. ► Epigenetic marks are observed after noxious stimulation within nociceptive pathways. ► DNMT and HDAC inhibitors can reduce pain behaviour.
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| Veröffentlicht in: | Current opinion in pharmacology 2012-02, Vol.12 (1), p.35-41 |
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| container_end_page | 41 |
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| container_start_page | 35 |
| container_title | Current opinion in pharmacology |
| container_volume | 12 |
| creator | Sandrine M, Geranton |
| description | Highlights ► Epigenetic mechanisms are engaged after injury and in chronic pain states. ► Epigenetic marks are observed after noxious stimulation within nociceptive pathways. ► DNMT and HDAC inhibitors can reduce pain behaviour. |
| doi_str_mv | 10.1016/j.coph.2011.10.012 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1471-4892 |
| ispartof | Current opinion in pharmacology, 2012-02, Vol.12 (1), p.35-41 |
| issn | 1471-4892 1471-4973 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Analgesics - therapeutic use Antineoplastic Agents - pharmacology Epigenesis, Genetic - physiology Humans Internal Medicine Learning Medical Education Pain - drug therapy Pain - metabolism Pain Management - methods |
| title | Targeting epigenetic mechanisms for pain relief |
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