Neonatal follow-up of 995 consecutively born children after embryo biopsy for PGD

BACKGROUND Outcome data on children born after assisted reproduction treatments are important for both patients and health-care providers. The objective of this study was to determine whether embryo biopsy as performed in PGD has an impact on the health of infants up to 2 months of age. METHODS A prospective comparative follow-up study of children born after PGD and children born after ICSI by collecting written reports and performing a physical examination at 2 months was performed. Auxological data at birth and physical findings up to 2 months of age were compared for 995 children consecutively live born after embryo biopsy (1994–2009) and for a control group of 1507 children born after ICSI with embryo transfer on Day 5. RESULTS No differences regarding mean term, prematurity (term