The Relationship Between Dysphagia, Pump Function, and Lower Esophageal Sphincter Pressures on High-Resolution Manometry

Introduction Study objective was to compare high-resolution impedance manometry (HRIM) findings between patients with and without dysphagia. Methods After Institutional Review Board approval, a prospectively maintained database was reviewed to identify patients who underwent HRIM. Patients without upper endoscopy within 7 days of manometry, patients with achalasia, history of previous foregut surgery, esophageal strictures, or a large hiatus hernia were excluded. A new parameter called lower esophageal sphincter pressure integral (LESPI) was compared between patients with and without dysphagia. For subanalysis, subjects were categorized: (a) group A: no dysphagia and 3,000 mmHg s cm. However, 32% of patients with