Respiratory control and sternohyoid muscle structure and function in aged male rats: Decreased susceptibility to chronic intermittent hypoxia

Highlights ► Chronic intermittent hypoxia (CIH) has no effect on baseline ventilation or ventilatory responses to acute hypoxia or hypercapnia. ► Sternohyoid (upper airway dilator) muscle myosin heavy chain fibre type and size, succinate dehydrogenase and glycerol-3-phosphate dehydrogenase enzyme ac...

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Veröffentlicht in:Respiratory physiology & neurobiology 2012-03, Vol.180 (2), p.175-182
Hauptverfasser: Skelly, J. Richard, Edge, Deirdre, Shortt, Christine M, Jones, James F.X, Bradford, Aidan, O’Halloran, Ken D
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container_end_page 182
container_issue 2
container_start_page 175
container_title Respiratory physiology & neurobiology
container_volume 180
creator Skelly, J. Richard
Edge, Deirdre
Shortt, Christine M
Jones, James F.X
Bradford, Aidan
O’Halloran, Ken D
description Highlights ► Chronic intermittent hypoxia (CIH) has no effect on baseline ventilation or ventilatory responses to acute hypoxia or hypercapnia. ► Sternohyoid (upper airway dilator) muscle myosin heavy chain fibre type and size, succinate dehydrogenase and glycerol-3-phosphate dehydrogenase enzyme activities are unaffected by CIH. ► CIH does not alter aged sternohyoid muscle force or fatigue.
doi_str_mv 10.1016/j.resp.2011.11.004
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subjects Aging - physiology
Animals
Body Weight - physiology
Chronic Disease
Control of breathing
Data Interpretation, Statistical
Electric Stimulation
Fibre type
Glyceraldehyde-3-Phosphate Dehydrogenases - metabolism
Heart - anatomy & histology
Heart - physiology
Hematocrit
Hypoxia
Hypoxia - physiopathology
Immunohistochemistry
Isometric Contraction - physiology
Male
Medical Education
Muscle Contraction - physiology
Muscle Fatigue - physiology
Myosin Heavy Chains - metabolism
Obstructive sleep apnoea syndrome
Organ Size - physiology
Oxygen Consumption - physiology
Pharyngeal Muscles - anatomy & histology
Pharyngeal Muscles - growth & development
Pharyngeal Muscles - physiology
Plethysmography, Whole Body
Pulmonary/Respiratory
Rats
Rats, Wistar
Respiratory Mechanics - physiology
Sternohyoid muscle
Succinate Dehydrogenase - metabolism
title Respiratory control and sternohyoid muscle structure and function in aged male rats: Decreased susceptibility to chronic intermittent hypoxia
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