Inspiratory-activated and inspiratory-inhibited airway vagal preganglionic neurons in the ventrolateral medulla of neonatal rat are different in intrinsic electrophysiological properties
Highlights ► Inspiratory-activated and inspiratory-inhibited AVPNs differ in architecture. ► Inspiratory-inhibited AVPNs has higher excitability under current clamp. ► Different K+ channels mediate the afterhyperpolarization in AVPNs. ► Different K+ channels mediate the voltage-gated lasting K+ curr...
Gespeichert in:
| Veröffentlicht in: | Respiratory physiology & neurobiology 2012-03, Vol.180 (2), p.323-330 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 330 |
|---|---|
| container_issue | 2 |
| container_start_page | 323 |
| container_title | Respiratory physiology & neurobiology |
| container_volume | 180 |
| creator | Chen, Yonghua Hou, Lili Zhou, Xujiao Qiu, Dongying Yuan, Wenjun Zhu, Lei Wang, Jijiang |
| description | Highlights ► Inspiratory-activated and inspiratory-inhibited AVPNs differ in architecture. ► Inspiratory-inhibited AVPNs has higher excitability under current clamp. ► Different K+ channels mediate the afterhyperpolarization in AVPNs. ► Different K+ channels mediate the voltage-gated lasting K+ currents in AVPNs. |
| doi_str_mv | 10.1016/j.resp.2011.12.014 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_920228471</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1569904811004356</els_id><sourcerecordid>1221146702</sourcerecordid><originalsourceid>FETCH-LOGICAL-c443t-ef2b909d9168be3b1df19251540f3f28840d0fca6ea488e4604f8cfd6e301d403</originalsourceid><addsrcrecordid>eNp9ks2KFDEUhQtRnHH0BVxI7XRTbW4qXT8gggz-DAy4UNchndx037YmKZOqln41n85b06OIi1klJN85l5yTongOYgUCmtf7VcI8rqQAWIFcCVAPinPo2q6CNfQPeb9u-qoXqjsrnuS8FwJaaOvHxZmUshatas6LX1chj5TMFNOxMnaig5nQlSa4kv65obCjDd3eUPppjuXBbM1Qjgm3JmwHioFsGXBOMWQWltMOywOGKcWB_RKjN-jmYTBl9MzFYCY-Y_PSJCwdeY-J8UVKrOLR7IcDWnYYd8dMcYhbsrcj44hpIsxPi0feDBmf3a0XxbcP779efqquP3-8unx3XVml6qlCLze96F0PTbfBegPOQy_XsFbC1152nRJOeGsaNKrrUDVC-c5612AtwClRXxQvT748-seMedI3lC3yY_ghc9a9FFJ2qgUmX91LgpQAqmmFZFSeUJtizgm9HhPdmHTUIPTSrt7rpV29tMtCze2y6MWd_7zhPP9K_tTJwJsTgJzHgTDpbAmDRUeJs9Qu0v3-b_-T24HCEvt3PGLexzkFTlqDzizQX5b_tXwvACFUvW7q33Uw0Vc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1221146702</pqid></control><display><type>article</type><title>Inspiratory-activated and inspiratory-inhibited airway vagal preganglionic neurons in the ventrolateral medulla of neonatal rat are different in intrinsic electrophysiological properties</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Chen, Yonghua ; Hou, Lili ; Zhou, Xujiao ; Qiu, Dongying ; Yuan, Wenjun ; Zhu, Lei ; Wang, Jijiang</creator><creatorcontrib>Chen, Yonghua ; Hou, Lili ; Zhou, Xujiao ; Qiu, Dongying ; Yuan, Wenjun ; Zhu, Lei ; Wang, Jijiang</creatorcontrib><description>Highlights ► Inspiratory-activated and inspiratory-inhibited AVPNs differ in architecture. ► Inspiratory-inhibited AVPNs has higher excitability under current clamp. ► Different K+ channels mediate the afterhyperpolarization in AVPNs. ► Different K+ channels mediate the voltage-gated lasting K+ currents in AVPNs.</description><identifier>ISSN: 1569-9048</identifier><identifier>EISSN: 1878-1519</identifier><identifier>DOI: 10.1016/j.resp.2011.12.014</identifier><identifier>PMID: 22230746</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Action potential ; Afterhyperpolarization ; Airway ; Animals ; Animals, Newborn ; Apamin ; Apamin - pharmacology ; Autonomic Fibers, Preganglionic - drug effects ; Autonomic Fibers, Preganglionic - physiology ; Brain Stem - physiology ; Charybdotoxin ; Charybdotoxin - pharmacology ; Depolarization ; Electrophysiological Phenomena ; Fluorescent Dyes ; Hypoglossal Nerve - physiology ; In Vitro Techniques ; Ion channel ; Ion channels ; Medical Education ; Medulla oblongata ; Medulla Oblongata - cytology ; Medulla Oblongata - drug effects ; Medulla Oblongata - physiology ; Membrane potential ; Neonates ; Nervous system ; Neurons ; nucleus ambiguus ; Patch clamp ; Patch-Clamp Techniques ; Potassium Channel Blockers - pharmacology ; Potassium channels (calcium-gated) ; Potassium Channels, Calcium-Activated - drug effects ; Potassium Channels, Calcium-Activated - physiology ; Potassium currents ; Preganglionic autonomic neurons ; Pulmonary/Respiratory ; Rats ; Respiratory Mechanics - physiology ; Respiratory tract ; Sodium currents ; Synapses - drug effects ; Synapses - physiology ; Trachea - innervation ; Trachea - physiology ; Vagus nerve ; Vagus Nerve - drug effects ; Vagus Nerve - physiology</subject><ispartof>Respiratory physiology & neurobiology, 2012-03, Vol.180 (2), p.323-330</ispartof><rights>Elsevier B.V.</rights><rights>2011 Elsevier B.V.</rights><rights>Copyright © 2011 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c443t-ef2b909d9168be3b1df19251540f3f28840d0fca6ea488e4604f8cfd6e301d403</citedby><cites>FETCH-LOGICAL-c443t-ef2b909d9168be3b1df19251540f3f28840d0fca6ea488e4604f8cfd6e301d403</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.resp.2011.12.014$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22230746$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chen, Yonghua</creatorcontrib><creatorcontrib>Hou, Lili</creatorcontrib><creatorcontrib>Zhou, Xujiao</creatorcontrib><creatorcontrib>Qiu, Dongying</creatorcontrib><creatorcontrib>Yuan, Wenjun</creatorcontrib><creatorcontrib>Zhu, Lei</creatorcontrib><creatorcontrib>Wang, Jijiang</creatorcontrib><title>Inspiratory-activated and inspiratory-inhibited airway vagal preganglionic neurons in the ventrolateral medulla of neonatal rat are different in intrinsic electrophysiological properties</title><title>Respiratory physiology & neurobiology</title><addtitle>Respir Physiol Neurobiol</addtitle><description>Highlights ► Inspiratory-activated and inspiratory-inhibited AVPNs differ in architecture. ► Inspiratory-inhibited AVPNs has higher excitability under current clamp. ► Different K+ channels mediate the afterhyperpolarization in AVPNs. ► Different K+ channels mediate the voltage-gated lasting K+ currents in AVPNs.</description><subject>Action potential</subject><subject>Afterhyperpolarization</subject><subject>Airway</subject><subject>Animals</subject><subject>Animals, Newborn</subject><subject>Apamin</subject><subject>Apamin - pharmacology</subject><subject>Autonomic Fibers, Preganglionic - drug effects</subject><subject>Autonomic Fibers, Preganglionic - physiology</subject><subject>Brain Stem - physiology</subject><subject>Charybdotoxin</subject><subject>Charybdotoxin - pharmacology</subject><subject>Depolarization</subject><subject>Electrophysiological Phenomena</subject><subject>Fluorescent Dyes</subject><subject>Hypoglossal Nerve - physiology</subject><subject>In Vitro Techniques</subject><subject>Ion channel</subject><subject>Ion channels</subject><subject>Medical Education</subject><subject>Medulla oblongata</subject><subject>Medulla Oblongata - cytology</subject><subject>Medulla Oblongata - drug effects</subject><subject>Medulla Oblongata - physiology</subject><subject>Membrane potential</subject><subject>Neonates</subject><subject>Nervous system</subject><subject>Neurons</subject><subject>nucleus ambiguus</subject><subject>Patch clamp</subject><subject>Patch-Clamp Techniques</subject><subject>Potassium Channel Blockers - pharmacology</subject><subject>Potassium channels (calcium-gated)</subject><subject>Potassium Channels, Calcium-Activated - drug effects</subject><subject>Potassium Channels, Calcium-Activated - physiology</subject><subject>Potassium currents</subject><subject>Preganglionic autonomic neurons</subject><subject>Pulmonary/Respiratory</subject><subject>Rats</subject><subject>Respiratory Mechanics - physiology</subject><subject>Respiratory tract</subject><subject>Sodium currents</subject><subject>Synapses - drug effects</subject><subject>Synapses - physiology</subject><subject>Trachea - innervation</subject><subject>Trachea - physiology</subject><subject>Vagus nerve</subject><subject>Vagus Nerve - drug effects</subject><subject>Vagus Nerve - physiology</subject><issn>1569-9048</issn><issn>1878-1519</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9ks2KFDEUhQtRnHH0BVxI7XRTbW4qXT8gggz-DAy4UNchndx037YmKZOqln41n85b06OIi1klJN85l5yTongOYgUCmtf7VcI8rqQAWIFcCVAPinPo2q6CNfQPeb9u-qoXqjsrnuS8FwJaaOvHxZmUshatas6LX1chj5TMFNOxMnaig5nQlSa4kv65obCjDd3eUPppjuXBbM1Qjgm3JmwHioFsGXBOMWQWltMOywOGKcWB_RKjN-jmYTBl9MzFYCY-Y_PSJCwdeY-J8UVKrOLR7IcDWnYYd8dMcYhbsrcj44hpIsxPi0feDBmf3a0XxbcP779efqquP3-8unx3XVml6qlCLze96F0PTbfBegPOQy_XsFbC1152nRJOeGsaNKrrUDVC-c5612AtwClRXxQvT748-seMedI3lC3yY_ghc9a9FFJ2qgUmX91LgpQAqmmFZFSeUJtizgm9HhPdmHTUIPTSrt7rpV29tMtCze2y6MWd_7zhPP9K_tTJwJsTgJzHgTDpbAmDRUeJs9Qu0v3-b_-T24HCEvt3PGLexzkFTlqDzizQX5b_tXwvACFUvW7q33Uw0Vc</recordid><startdate>20120315</startdate><enddate>20120315</enddate><creator>Chen, Yonghua</creator><creator>Hou, Lili</creator><creator>Zhou, Xujiao</creator><creator>Qiu, Dongying</creator><creator>Yuan, Wenjun</creator><creator>Zhu, Lei</creator><creator>Wang, Jijiang</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>20120315</creationdate><title>Inspiratory-activated and inspiratory-inhibited airway vagal preganglionic neurons in the ventrolateral medulla of neonatal rat are different in intrinsic electrophysiological properties</title><author>Chen, Yonghua ; Hou, Lili ; Zhou, Xujiao ; Qiu, Dongying ; Yuan, Wenjun ; Zhu, Lei ; Wang, Jijiang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c443t-ef2b909d9168be3b1df19251540f3f28840d0fca6ea488e4604f8cfd6e301d403</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Action potential</topic><topic>Afterhyperpolarization</topic><topic>Airway</topic><topic>Animals</topic><topic>Animals, Newborn</topic><topic>Apamin</topic><topic>Apamin - pharmacology</topic><topic>Autonomic Fibers, Preganglionic - drug effects</topic><topic>Autonomic Fibers, Preganglionic - physiology</topic><topic>Brain Stem - physiology</topic><topic>Charybdotoxin</topic><topic>Charybdotoxin - pharmacology</topic><topic>Depolarization</topic><topic>Electrophysiological Phenomena</topic><topic>Fluorescent Dyes</topic><topic>Hypoglossal Nerve - physiology</topic><topic>In Vitro Techniques</topic><topic>Ion channel</topic><topic>Ion channels</topic><topic>Medical Education</topic><topic>Medulla oblongata</topic><topic>Medulla Oblongata - cytology</topic><topic>Medulla Oblongata - drug effects</topic><topic>Medulla Oblongata - physiology</topic><topic>Membrane potential</topic><topic>Neonates</topic><topic>Nervous system</topic><topic>Neurons</topic><topic>nucleus ambiguus</topic><topic>Patch clamp</topic><topic>Patch-Clamp Techniques</topic><topic>Potassium Channel Blockers - pharmacology</topic><topic>Potassium channels (calcium-gated)</topic><topic>Potassium Channels, Calcium-Activated - drug effects</topic><topic>Potassium Channels, Calcium-Activated - physiology</topic><topic>Potassium currents</topic><topic>Preganglionic autonomic neurons</topic><topic>Pulmonary/Respiratory</topic><topic>Rats</topic><topic>Respiratory Mechanics - physiology</topic><topic>Respiratory tract</topic><topic>Sodium currents</topic><topic>Synapses - drug effects</topic><topic>Synapses - physiology</topic><topic>Trachea - innervation</topic><topic>Trachea - physiology</topic><topic>Vagus nerve</topic><topic>Vagus Nerve - drug effects</topic><topic>Vagus Nerve - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chen, Yonghua</creatorcontrib><creatorcontrib>Hou, Lili</creatorcontrib><creatorcontrib>Zhou, Xujiao</creatorcontrib><creatorcontrib>Qiu, Dongying</creatorcontrib><creatorcontrib>Yuan, Wenjun</creatorcontrib><creatorcontrib>Zhu, Lei</creatorcontrib><creatorcontrib>Wang, Jijiang</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Respiratory physiology & neurobiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chen, Yonghua</au><au>Hou, Lili</au><au>Zhou, Xujiao</au><au>Qiu, Dongying</au><au>Yuan, Wenjun</au><au>Zhu, Lei</au><au>Wang, Jijiang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Inspiratory-activated and inspiratory-inhibited airway vagal preganglionic neurons in the ventrolateral medulla of neonatal rat are different in intrinsic electrophysiological properties</atitle><jtitle>Respiratory physiology & neurobiology</jtitle><addtitle>Respir Physiol Neurobiol</addtitle><date>2012-03-15</date><risdate>2012</risdate><volume>180</volume><issue>2</issue><spage>323</spage><epage>330</epage><pages>323-330</pages><issn>1569-9048</issn><eissn>1878-1519</eissn><abstract>Highlights ► Inspiratory-activated and inspiratory-inhibited AVPNs differ in architecture. ► Inspiratory-inhibited AVPNs has higher excitability under current clamp. ► Different K+ channels mediate the afterhyperpolarization in AVPNs. ► Different K+ channels mediate the voltage-gated lasting K+ currents in AVPNs.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>22230746</pmid><doi>10.1016/j.resp.2011.12.014</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1569-9048 |
| ispartof | Respiratory physiology & neurobiology, 2012-03, Vol.180 (2), p.323-330 |
| issn | 1569-9048 1878-1519 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_920228471 |
| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Action potential Afterhyperpolarization Airway Animals Animals, Newborn Apamin Apamin - pharmacology Autonomic Fibers, Preganglionic - drug effects Autonomic Fibers, Preganglionic - physiology Brain Stem - physiology Charybdotoxin Charybdotoxin - pharmacology Depolarization Electrophysiological Phenomena Fluorescent Dyes Hypoglossal Nerve - physiology In Vitro Techniques Ion channel Ion channels Medical Education Medulla oblongata Medulla Oblongata - cytology Medulla Oblongata - drug effects Medulla Oblongata - physiology Membrane potential Neonates Nervous system Neurons nucleus ambiguus Patch clamp Patch-Clamp Techniques Potassium Channel Blockers - pharmacology Potassium channels (calcium-gated) Potassium Channels, Calcium-Activated - drug effects Potassium Channels, Calcium-Activated - physiology Potassium currents Preganglionic autonomic neurons Pulmonary/Respiratory Rats Respiratory Mechanics - physiology Respiratory tract Sodium currents Synapses - drug effects Synapses - physiology Trachea - innervation Trachea - physiology Vagus nerve Vagus Nerve - drug effects Vagus Nerve - physiology |
| title | Inspiratory-activated and inspiratory-inhibited airway vagal preganglionic neurons in the ventrolateral medulla of neonatal rat are different in intrinsic electrophysiological properties |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T10%3A39%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Inspiratory-activated%20and%20inspiratory-inhibited%20airway%20vagal%20preganglionic%20neurons%20in%20the%20ventrolateral%20medulla%20of%20neonatal%20rat%20are%20different%20in%20intrinsic%20electrophysiological%20properties&rft.jtitle=Respiratory%20physiology%20&%20neurobiology&rft.au=Chen,%20Yonghua&rft.date=2012-03-15&rft.volume=180&rft.issue=2&rft.spage=323&rft.epage=330&rft.pages=323-330&rft.issn=1569-9048&rft.eissn=1878-1519&rft_id=info:doi/10.1016/j.resp.2011.12.014&rft_dat=%3Cproquest_cross%3E1221146702%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1221146702&rft_id=info:pmid/22230746&rft_els_id=S1569904811004356&rfr_iscdi=true |