Heterogeneity and Homogeneity Across the Autism Spectrum: The Role of Development

Autism is a strongly genetic disorder and de novo mutations may play a causal role in a relatively large percentage of individuals with the disease. It is discussed how altered development may be an important factor that forces diverse genetic vulnerabilities into common syndromic presentation in au...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of the American Academy of Child and Adolescent Psychiatry 2009-05, Vol.48 (5), p.471-473
Hauptverfasser:	Lombroso, Paul J., M.D, Ogren, Marilee P., Ph.D, Jones, Warren, B.A, Klin, Ami, Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Attention Autism Autistic Disorder - genetics Autistic Disorder - psychology Biological and medical sciences Child clinical studies Child Development Child, Preschool Children & youth Developmental disorders Developmental psychology Developmental Stages Female Fixation, Ocular Genetic Disorders Genetic Heterogeneity Genetics Genomics Heterogeneity Humans Infant Infant, Newborn Infantile autism Interpersonal Relations Male Medical sciences Medical treatment Pediatrics Pervasive Developmental Disorders Phenotypes Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Severity Social Adjustment Studies Symptoms Symptoms (Individual Disorders) Variability
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Autism is a strongly genetic disorder and de novo mutations may play a causal role in a relatively large percentage of individuals with the disease. It is discussed how altered development may be an important factor that forces diverse genetic vulnerabilities into common syndromic presentation in autism.
ISSN:	0890-8567 1527-5418
DOI:	10.1097/CHI.0b013e31819f6c0d