Prognostic Value of Uric Acid in Patients With ST-Elevated Myocardial Infarction Undergoing Primary Coronary Intervention

Elevated uric acid (UA) levels have been associated with cardiovascular disease in epidemiologic studies. The relation between UA levels and long-term outcomes in patients with ST-segment elevation myocardial infarction who undergo primary percutaneous coronary intervention is not known. Data from 2...

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Veröffentlicht in:	The American journal of cardiology 2012-02, Vol.109 (4), p.486-491
Hauptverfasser:	Kaya, Mehmet G., MD, Uyarel, Huseyin, MD, Akpek, Mahmut, MD, Kalay, Nihat, MD, Ergelen, Mehmet, MD, Ayhan, Erkan, MD, Isik, Turgay, MD, Cicek, Gokhan, MD, Elcik, Deniz, MD, Sahin, Ömer, MD, Cosgun, Said M., MD, Oguzhan, Abdurrahman, MD, Eren, Mehmet, MD, Gibson, C. Michael, MS, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Age Factors Angioplasty, Balloon, Coronary Biological and medical sciences Cardiology Cardiology. Vascular system Cardiovascular Clinical outcomes Coronary heart disease Diabetes Mellitus - epidemiology Female Follow-Up Studies Heart Heart attacks Heart Failure - epidemiology Hospital Mortality Humans Length of Stay - statistics & numerical data Male Medical prognosis Medical sciences Medical treatment Middle Aged Multivariate Analysis Myocardial Infarction - therapy Myocarditis. Cardiomyopathies Prognosis Recurrence Retreatment Uric Acid - blood
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Zusammenfassung:	Elevated uric acid (UA) levels have been associated with cardiovascular disease in epidemiologic studies. The relation between UA levels and long-term outcomes in patients with ST-segment elevation myocardial infarction who undergo primary percutaneous coronary intervention is not known. Data from 2,249 consecutive patients with ST-segment elevation myocardial infarction who underwent primary percutaneous coronary intervention were evaluated. Patients were divided into 2 groups with high or low UA using upper limits of normal of 6 mg/dl for women and 7 mg/dl for men. There were 1,643 patients in the low-UA group (mean age 55.9 ± 11.6 years, 85% men) and 606 patients in the high-UA group (mean age 60.5 ± 12.6 years, 76% men). Serum UA levels were 8.0 ± 1.5 mg/dl in the high-UA group and 5.2 ± 1.0 mg/dl in the low-UA group (p
ISSN:	0002-9149 1879-1913
DOI:	10.1016/j.amjcard.2011.09.042