The tumor suppressor HACE1 targets Rac1 to ubiquitin-mediated proteasomal degradation

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:M.S. Médecine sciences 2012-01, Vol.28 (1), p.39-41
Hauptverfasser: Gacon, Gérard, Mettouchi, Amel, Lemichez, Emmanuel
Format: Artikel
Sprache:fre
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 41
container_issue 1
container_start_page 39
container_title M.S. Médecine sciences
container_volume 28
creator Gacon, Gérard
Mettouchi, Amel
Lemichez, Emmanuel
description
doi_str_mv 10.1051/medsci/2012281014
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_919226749</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>919226749</sourcerecordid><originalsourceid>FETCH-LOGICAL-p140t-b7cf5689e807e1c59fe1d1eccd4eaf785ffc6de18445b4a4553dff7f8de75933</originalsourceid><addsrcrecordid>eNo1kLFOwzAQhj2AaCk8AAvKxhRqO3Zsj1VVKFIlJBTmyLHPxShp0tgeeHssUaa7kz799-lH6IHgZ4I5WQ9gg_FrigmlkmDCrtASi1qUWAm2QLchfGNMCafVDVrQzChJ5RJ9Nl9QxDSMcxHSNM0QQl73m-2OFFHPR4ih-NAmH2OROn9OPvpTmZ95HcEW0zxG0GEcdF9YOM7a6ujH0x26droPcH-ZK9S87Jrtvjy8v75tN4dyIgzHshPG8VoqkFgAMVw5IJaAMZaBdkJy50xtgUjGeMc047yyzgknLQiuqmqFnv5is8Y5QYjt4IOBvtcnGFNoFVGU1oKpTD5eyNRl-Xaa_aDnn_a_iOoX59VgrA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>919226749</pqid></control><display><type>article</type><title>The tumor suppressor HACE1 targets Rac1 to ubiquitin-mediated proteasomal degradation</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><creator>Gacon, Gérard ; Mettouchi, Amel ; Lemichez, Emmanuel</creator><creatorcontrib>Gacon, Gérard ; Mettouchi, Amel ; Lemichez, Emmanuel</creatorcontrib><identifier>ISSN: 0767-0974</identifier><identifier>DOI: 10.1051/medsci/2012281014</identifier><identifier>PMID: 22289828</identifier><language>fre</language><publisher>France</publisher><subject>Aminoquinolines - pharmacology ; Aminoquinolines - therapeutic use ; Animals ; Antineoplastic Agents - pharmacology ; Antineoplastic Agents - therapeutic use ; Bacterial Toxins - pharmacology ; Enzyme Inhibitors - pharmacology ; Enzyme Inhibitors - therapeutic use ; Escherichia coli Proteins - pharmacology ; Genes, Tumor Suppressor ; Humans ; Kidney Neoplasms - genetics ; Kidney Neoplasms - metabolism ; Mice ; Neoplasm Proteins - antagonists &amp; inhibitors ; Neoplasm Proteins - physiology ; Neoplasms - genetics ; Neoplasms - metabolism ; Neuropeptides - antagonists &amp; inhibitors ; Neuropeptides - physiology ; Proteasome Endopeptidase Complex - metabolism ; Protein Processing, Post-Translational ; Pyrimidines - pharmacology ; Pyrimidines - therapeutic use ; rac GTP-Binding Proteins - antagonists &amp; inhibitors ; rac GTP-Binding Proteins - physiology ; rac1 GTP-Binding Protein - metabolism ; rho GTP-Binding Proteins - metabolism ; RNA Interference ; Tumor Suppressor Proteins - antagonists &amp; inhibitors ; Tumor Suppressor Proteins - physiology ; Ubiquitin - metabolism ; Ubiquitin-Protein Ligases - antagonists &amp; inhibitors ; Ubiquitin-Protein Ligases - genetics ; Ubiquitin-Protein Ligases - physiology ; Ubiquitination ; Wilms Tumor - genetics ; Wilms Tumor - metabolism</subject><ispartof>M.S. Médecine sciences, 2012-01, Vol.28 (1), p.39-41</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22289828$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gacon, Gérard</creatorcontrib><creatorcontrib>Mettouchi, Amel</creatorcontrib><creatorcontrib>Lemichez, Emmanuel</creatorcontrib><title>The tumor suppressor HACE1 targets Rac1 to ubiquitin-mediated proteasomal degradation</title><title>M.S. Médecine sciences</title><addtitle>Med Sci (Paris)</addtitle><subject>Aminoquinolines - pharmacology</subject><subject>Aminoquinolines - therapeutic use</subject><subject>Animals</subject><subject>Antineoplastic Agents - pharmacology</subject><subject>Antineoplastic Agents - therapeutic use</subject><subject>Bacterial Toxins - pharmacology</subject><subject>Enzyme Inhibitors - pharmacology</subject><subject>Enzyme Inhibitors - therapeutic use</subject><subject>Escherichia coli Proteins - pharmacology</subject><subject>Genes, Tumor Suppressor</subject><subject>Humans</subject><subject>Kidney Neoplasms - genetics</subject><subject>Kidney Neoplasms - metabolism</subject><subject>Mice</subject><subject>Neoplasm Proteins - antagonists &amp; inhibitors</subject><subject>Neoplasm Proteins - physiology</subject><subject>Neoplasms - genetics</subject><subject>Neoplasms - metabolism</subject><subject>Neuropeptides - antagonists &amp; inhibitors</subject><subject>Neuropeptides - physiology</subject><subject>Proteasome Endopeptidase Complex - metabolism</subject><subject>Protein Processing, Post-Translational</subject><subject>Pyrimidines - pharmacology</subject><subject>Pyrimidines - therapeutic use</subject><subject>rac GTP-Binding Proteins - antagonists &amp; inhibitors</subject><subject>rac GTP-Binding Proteins - physiology</subject><subject>rac1 GTP-Binding Protein - metabolism</subject><subject>rho GTP-Binding Proteins - metabolism</subject><subject>RNA Interference</subject><subject>Tumor Suppressor Proteins - antagonists &amp; inhibitors</subject><subject>Tumor Suppressor Proteins - physiology</subject><subject>Ubiquitin - metabolism</subject><subject>Ubiquitin-Protein Ligases - antagonists &amp; inhibitors</subject><subject>Ubiquitin-Protein Ligases - genetics</subject><subject>Ubiquitin-Protein Ligases - physiology</subject><subject>Ubiquitination</subject><subject>Wilms Tumor - genetics</subject><subject>Wilms Tumor - metabolism</subject><issn>0767-0974</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kLFOwzAQhj2AaCk8AAvKxhRqO3Zsj1VVKFIlJBTmyLHPxShp0tgeeHssUaa7kz799-lH6IHgZ4I5WQ9gg_FrigmlkmDCrtASi1qUWAm2QLchfGNMCafVDVrQzChJ5RJ9Nl9QxDSMcxHSNM0QQl73m-2OFFHPR4ih-NAmH2OROn9OPvpTmZ95HcEW0zxG0GEcdF9YOM7a6ujH0x26droPcH-ZK9S87Jrtvjy8v75tN4dyIgzHshPG8VoqkFgAMVw5IJaAMZaBdkJy50xtgUjGeMc047yyzgknLQiuqmqFnv5is8Y5QYjt4IOBvtcnGFNoFVGU1oKpTD5eyNRl-Xaa_aDnn_a_iOoX59VgrA</recordid><startdate>201201</startdate><enddate>201201</enddate><creator>Gacon, Gérard</creator><creator>Mettouchi, Amel</creator><creator>Lemichez, Emmanuel</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201201</creationdate><title>The tumor suppressor HACE1 targets Rac1 to ubiquitin-mediated proteasomal degradation</title><author>Gacon, Gérard ; Mettouchi, Amel ; Lemichez, Emmanuel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p140t-b7cf5689e807e1c59fe1d1eccd4eaf785ffc6de18445b4a4553dff7f8de75933</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>fre</language><creationdate>2012</creationdate><topic>Aminoquinolines - pharmacology</topic><topic>Aminoquinolines - therapeutic use</topic><topic>Animals</topic><topic>Antineoplastic Agents - pharmacology</topic><topic>Antineoplastic Agents - therapeutic use</topic><topic>Bacterial Toxins - pharmacology</topic><topic>Enzyme Inhibitors - pharmacology</topic><topic>Enzyme Inhibitors - therapeutic use</topic><topic>Escherichia coli Proteins - pharmacology</topic><topic>Genes, Tumor Suppressor</topic><topic>Humans</topic><topic>Kidney Neoplasms - genetics</topic><topic>Kidney Neoplasms - metabolism</topic><topic>Mice</topic><topic>Neoplasm Proteins - antagonists &amp; inhibitors</topic><topic>Neoplasm Proteins - physiology</topic><topic>Neoplasms - genetics</topic><topic>Neoplasms - metabolism</topic><topic>Neuropeptides - antagonists &amp; inhibitors</topic><topic>Neuropeptides - physiology</topic><topic>Proteasome Endopeptidase Complex - metabolism</topic><topic>Protein Processing, Post-Translational</topic><topic>Pyrimidines - pharmacology</topic><topic>Pyrimidines - therapeutic use</topic><topic>rac GTP-Binding Proteins - antagonists &amp; inhibitors</topic><topic>rac GTP-Binding Proteins - physiology</topic><topic>rac1 GTP-Binding Protein - metabolism</topic><topic>rho GTP-Binding Proteins - metabolism</topic><topic>RNA Interference</topic><topic>Tumor Suppressor Proteins - antagonists &amp; inhibitors</topic><topic>Tumor Suppressor Proteins - physiology</topic><topic>Ubiquitin - metabolism</topic><topic>Ubiquitin-Protein Ligases - antagonists &amp; inhibitors</topic><topic>Ubiquitin-Protein Ligases - genetics</topic><topic>Ubiquitin-Protein Ligases - physiology</topic><topic>Ubiquitination</topic><topic>Wilms Tumor - genetics</topic><topic>Wilms Tumor - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gacon, Gérard</creatorcontrib><creatorcontrib>Mettouchi, Amel</creatorcontrib><creatorcontrib>Lemichez, Emmanuel</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>M.S. Médecine sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gacon, Gérard</au><au>Mettouchi, Amel</au><au>Lemichez, Emmanuel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The tumor suppressor HACE1 targets Rac1 to ubiquitin-mediated proteasomal degradation</atitle><jtitle>M.S. Médecine sciences</jtitle><addtitle>Med Sci (Paris)</addtitle><date>2012-01</date><risdate>2012</risdate><volume>28</volume><issue>1</issue><spage>39</spage><epage>41</epage><pages>39-41</pages><issn>0767-0974</issn><cop>France</cop><pmid>22289828</pmid><doi>10.1051/medsci/2012281014</doi><tpages>3</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0767-0974
ispartof M.S. Médecine sciences, 2012-01, Vol.28 (1), p.39-41
issn 0767-0974
language fre
recordid cdi_proquest_miscellaneous_919226749
source MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
subjects Aminoquinolines - pharmacology
Aminoquinolines - therapeutic use
Animals
Antineoplastic Agents - pharmacology
Antineoplastic Agents - therapeutic use
Bacterial Toxins - pharmacology
Enzyme Inhibitors - pharmacology
Enzyme Inhibitors - therapeutic use
Escherichia coli Proteins - pharmacology
Genes, Tumor Suppressor
Humans
Kidney Neoplasms - genetics
Kidney Neoplasms - metabolism
Mice
Neoplasm Proteins - antagonists & inhibitors
Neoplasm Proteins - physiology
Neoplasms - genetics
Neoplasms - metabolism
Neuropeptides - antagonists & inhibitors
Neuropeptides - physiology
Proteasome Endopeptidase Complex - metabolism
Protein Processing, Post-Translational
Pyrimidines - pharmacology
Pyrimidines - therapeutic use
rac GTP-Binding Proteins - antagonists & inhibitors
rac GTP-Binding Proteins - physiology
rac1 GTP-Binding Protein - metabolism
rho GTP-Binding Proteins - metabolism
RNA Interference
Tumor Suppressor Proteins - antagonists & inhibitors
Tumor Suppressor Proteins - physiology
Ubiquitin - metabolism
Ubiquitin-Protein Ligases - antagonists & inhibitors
Ubiquitin-Protein Ligases - genetics
Ubiquitin-Protein Ligases - physiology
Ubiquitination
Wilms Tumor - genetics
Wilms Tumor - metabolism
title The tumor suppressor HACE1 targets Rac1 to ubiquitin-mediated proteasomal degradation
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T11%3A18%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20tumor%20suppressor%20HACE1%20targets%20Rac1%20to%20ubiquitin-mediated%20proteasomal%20degradation&rft.jtitle=M.S.%20M%C3%A9decine%20sciences&rft.au=Gacon,%20G%C3%A9rard&rft.date=2012-01&rft.volume=28&rft.issue=1&rft.spage=39&rft.epage=41&rft.pages=39-41&rft.issn=0767-0974&rft_id=info:doi/10.1051/medsci/2012281014&rft_dat=%3Cproquest_pubme%3E919226749%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=919226749&rft_id=info:pmid/22289828&rfr_iscdi=true