Vaginal progesterone in women with an asymptomatic sonographic short cervix in the midtrimester decreases preterm delivery and neonatal morbidity: a systematic review and metaanalysis of individual patient data

Objective To determine whether the use of vaginal progesterone in asymptomatic women with a sonographic short cervix (≤25 mm) in the midtrimester reduces the risk of preterm birth and improves neonatal morbidity and mortality. Study Design Individual patient data metaanalysis of randomized controlle...

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Veröffentlicht in:	American journal of obstetrics and gynecology 2012-02, Vol.206 (2), p.124.e1-124.e19
Hauptverfasser:	Romero, Roberto, MD, Nicolaides, Kypros, MD, Conde-Agudelo, Agustin, MD, MPH, Tabor, Ann, MD, O'Brien, John M., MD, Cetingoz, Elcin, MD, Da Fonseca, Eduardo, MD, Creasy, George W., MD, Klein, Katharina, MD, Rode, Line, MD, Soma-Pillay, Priya, MD, Fusey, Shalini, MD, Cam, Cetin, MD, Alfirevic, Zarko, MD, Hassan, Sonia S., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	17α-hydroxyprogesterone caproate Administration, Intravaginal admission to neonatal intensive care unit Biological and medical sciences birthweight <1500 g Diseases of mother, fetus and pregnancy Female Gynecology. Andrology. Obstetrics Humans mechanical ventilation Medical sciences Obstetrics and Gynecology Pregnancy Pregnancy Trimester, Second Pregnancy. Fetus. Placenta Premature Birth - prevention & control prematurity preterm birth Progesterone - administration & dosage Progesterone - therapeutic use progestin Progestins - therapeutic use respiratory distress syndrome Risk transvaginal ultrasound Treatment Outcome uterine cervix
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