A successful strategy for the use of synergistic intravenous streptomycin in a hemodialysis patient with refractory Enterococcus faecalis bacteremia

A successful strategy for the use of synergistic intravenous streptomycin in a hemodialysis patient with refractory Enterococcus faecalis bacteremia

Abstract Streptomycin has been available for over 60 years, yet optimal dosing in hemodialysis (HD) patients is not well defined. We report the successful treatment of enterococcal bacteremia in an HD patient with intravenous (IV) penicillin G and IV streptomycin at a dose of 7.5 mg/kg after HD sess...

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Veröffentlicht in:Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2011-10, Vol.17 (5), p.698-699
Hauptverfasser: Young, Heather, Jenkins, Timothy C, Belknap, Robert, Swartwood, Claire J
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Anti-Bacterial Agents - administration & dosage
Bacteremia
Bacteremia - complications
Bacteremia - diagnosis
Bacteremia - drug therapy
Case Report
Drug Synergism
Enterococcus
Enterococcus faecalis
Enterococcus faecalis - isolation & purification
Female
Gram-Positive Bacterial Infections - complications
Gram-Positive Bacterial Infections - diagnosis
Gram-Positive Bacterial Infections - drug therapy
Hematology, Oncology and Palliative Medicine
Hemodialysis
Humans
Infectious Diseases
Infusions, Intravenous
Intravenous streptomycin
Medical Microbiology
Medicine
Medicine & Public Health
Penicillin G - administration & dosage
Renal Dialysis
Streptomycin - administration & dosage
Virology
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Zusammenfassung:Abstract Streptomycin has been available for over 60 years, yet optimal dosing in hemodialysis (HD) patients is not well defined. We report the successful treatment of enterococcal bacteremia in an HD patient with intravenous (IV) penicillin G and IV streptomycin at a dose of 7.5 mg/kg after HD sessions.
ISSN:1341-321X
1437-7780
DOI:10.1007/s10156-011-0226-1