Propofol Infusion Syndrome: An Algorithm for Prevention

A slightly longer recovery from propofol therapy has been reported with long-term infusions.2 A Level 1 Tennessee trauma center reported six cases of propofol infusion syndrome over a 3-year period with high morbidity and mortality (Croce MA, personal communication, September 15, 2010). Since initia...

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Veröffentlicht in:	The American surgeon 2011-12, Vol.77 (12), p.1714-1715
Hauptverfasser:	TESTERMAN, George M, CHOW, Thomas T, EASPARAM, Sarah
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidosis - chemically induced Acute Kidney Injury - chemically induced Adolescent Adult Anesthesia, Intravenous - adverse effects Anesthetics, Intravenous - administration & dosage Anesthetics, Intravenous - adverse effects Biological and medical sciences Brain damage Descriptive labeling Drug dosages Fatal Outcome General aspects Humans Infusions, Intravenous Male Medical sciences Medical treatment Metabolites Mortality Prevention and actions Propofol - administration & dosage Propofol - adverse effects Public health. Hygiene Public health. Hygiene-occupational medicine Rhabdomyolysis - chemically induced Syndrome Trauma
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Zusammenfassung:	A slightly longer recovery from propofol therapy has been reported with long-term infusions.2 A Level 1 Tennessee trauma center reported six cases of propofol infusion syndrome over a 3-year period with high morbidity and mortality (Croce MA, personal communication, September 15, 2010). Since initiation of daily screening with serum lactate levels and creatine phosphokinase (CPK) levels, no further PRIS cases have been seen.
ISSN:	0003-1348 1555-9823
DOI:	10.1177/000313481107701250