Analgesic and Antiinflammatory Activity of Kaur-16-en-19-oic acid from Annona reticulata L. Bark

Kaur‐16‐en‐19‐oic acid was isolated from the bark of Annona reticulata and studied for its analgesic and antiinflammatory activity. Analgesic activity was assessed using the hot plate test and acetic acid‐induced writhing, and the antiinflammatory activity using the carrageenan induced rat paw oedem...

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Veröffentlicht in:	Phytotherapy research 2012-02, Vol.26 (2), p.273-276
Hauptverfasser:	Chavan, Machindra J., Kolhe, Dinesh R., Wakte, Pravin S., Shinde, Devanand B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic Acid analgesic Analgesics - pharmacology Animals Annona - chemistry Annona reticulata Anti-Inflammatory Agents - pharmacology antiinflammatory bark Biological and medical sciences Carrageenan Diterpenes - pharmacology General pharmacology kaur-16-en-19-oic acid Male Medical sciences Mice Pain - drug therapy Pain Measurement Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Bark - chemistry Plant Extracts - pharmacology Rats Rats, Wistar
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Zusammenfassung:	Kaur‐16‐en‐19‐oic acid was isolated from the bark of Annona reticulata and studied for its analgesic and antiinflammatory activity. Analgesic activity was assessed using the hot plate test and acetic acid‐induced writhing, and the antiinflammatory activity using the carrageenan induced rat paw oedema method. Kaur‐16‐en‐19‐oic acid, at doses of 10 and 20 mg/kg, exhibited significant (p
ISSN:	0951-418X 1099-1573
DOI:	10.1002/ptr.3544