Neoadjuvant chemoradiotherapy followed by surgery for esophageal adenocarcinoma: Significance of microscopically positive circumferential radial margins

Objectives The incidence and consequence of an isolated involved circumferential radial margin (CRM) after resection for esophageal adenocarcinoma in the setting of neoadjuvant chemoradiotherapy (CRT) has not been reported. We aimed to determine the frequency and significance of a close (

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Bibliographische Detailangaben
Veröffentlicht in:	The Journal of thoracic and cardiovascular surgery 2012-02, Vol.143 (2), p.412-420
Hauptverfasser:	Harvin, John A., MD, Lahat, Guy, MD, Correa, Arlene M., PhD, Lee, Jared, MS, Maru, Dipen, MD, Ajani, Jaffer, MD, Marom, Edith M., MD, Welsh, James, MD, Bhutani, Manoop S., MD, Walsh, Garret, MD, Roth, Jack, MD, Mehran, Reza, MD, Vaporciyan, Ara, MD, Rice, David, MD, Swisher, Stephen, MD, Hofstetter, Wayne, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - mortality Adenocarcinoma - pathology Adenocarcinoma - therapy Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Cardiology. Vascular system Cardiothoracic Surgery Chemoradiotherapy, Adjuvant Chi-Square Distribution Disease-Free Survival Esophageal Neoplasms - mortality Esophageal Neoplasms - pathology Esophageal Neoplasms - therapy Esophagectomy - adverse effects Esophagectomy - mortality Esophagus Gastroenterology. Liver. Pancreas. Abdomen Humans Kaplan-Meier Estimate Logistic Models Medical sciences Neoadjuvant Therapy Neoplasm Recurrence, Local Neoplasm, Residual Pneumology Propensity Score Proportional Hazards Models Retrospective Studies Risk Assessment Risk Factors Survival Rate Texas Time Factors Treatment Outcome Tumors
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Beschreibung
Zusammenfassung:	Objectives The incidence and consequence of an isolated involved circumferential radial margin (CRM) after resection for esophageal adenocarcinoma in the setting of neoadjuvant chemoradiotherapy (CRT) has not been reported. We aimed to determine the frequency and significance of a close (
ISSN:	0022-5223 1097-685X
DOI:	10.1016/j.jtcvs.2011.10.044