Sulfo-click reaction via in situ generated thioacids and its application in kinetic target-guided synthesis
Herein, we describe a practical, one-pot variant of the sulfo-click reaction, in which 9-fluorenylmethyl-protected thioesters are rapidly deprotected and reacted further with sulfonylazides to give N-acyl sulfonamides.
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Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2012-01, Vol.48 (10), p.1526-1528 |
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container_title | Chemical communications (Cambridge, England) |
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creator | Namelikonda, Niranjan Kumar Manetsch, Roman |
description | Herein, we describe a practical, one-pot variant of the sulfo-click reaction, in which 9-fluorenylmethyl-protected thioesters are rapidly deprotected and reacted further with sulfonylazides to give N-acyl sulfonamides. |
doi_str_mv | 10.1039/c1cc14724b |
format | Article |
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source | MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
subjects | Azides - chemistry Click Chemistry Esters - chemical synthesis Esters - chemistry Kinetics Molecular Structure Sulfhydryl Compounds - chemistry Sulfonamides - chemical synthesis Sulfonamides - chemistry |
title | Sulfo-click reaction via in situ generated thioacids and its application in kinetic target-guided synthesis |
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