Comparable efficacy of a topical 0.0584% hydrocortisone aceponate spray and oral ciclosporin in treating canine atopic dermatitis

This study compared the efficacy of a 0.0584% hydrocortisone aceponate (HCA) spray (Cortavance®; Virbac SA) and ciclosporin (Atopica®; Novartis Animal Health) in canine atopic dermatitis in a single‐blind randomized controlled trial. Dogs received HCA (two sprays/100 cm2; n = 24) or ciclosporin (5 m...

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Veröffentlicht in:	Veterinary dermatology 2012-02, Vol.23 (1), p.4-e2
Hauptverfasser:	Nuttall, Tim J., McEwan, Neil A., Bensignor, Emmanuel, Cornegliani, Luisa, Löwenstein, Christine, Rème, Christophe A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Administration, Topical Aerosols Animals Cyclosporine - administration & dosage Dermatitis, Atopic - drug therapy Dermatitis, Atopic - veterinary Dermatologic Agents - administration & dosage Dog Diseases - drug therapy Dogs Female Hydrocortisone - administration & dosage Hydrocortisone - analogs & derivatives Male Single-Blind Method Treatment Outcome
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Zusammenfassung:	This study compared the efficacy of a 0.0584% hydrocortisone aceponate (HCA) spray (Cortavance®; Virbac SA) and ciclosporin (Atopica®; Novartis Animal Health) in canine atopic dermatitis in a single‐blind randomized controlled trial. Dogs received HCA (two sprays/100 cm2; n = 24) or ciclosporin (5 mg/kg; n = 21). Canine Atopic Dermatitis Extent and Severity Index (CADESI)‐03, pruritus (visual analog scale with grade descriptors) and owner scores (5‐point scales) were recorded every 28 days for 84 days. Intention‐to‐treat data were analysed. CADESI‐03 and pruritus significantly decreased over time (P
ISSN:	0959-4493 1365-3164
DOI:	10.1111/j.1365-3164.2011.00992.x