Old World Leishmania infantum Cutaneous Leishmaniasis Unresponsive to Liposomal Amphotericin B Treated With Topical Imiquimod

We present a case of a child with Leishmania infantum cutaneous leishmaniasis unresponsive to 2 courses of intravenous liposomal amphotericin B, a treatment failure that has not been reported in this Leishmania species. The patient responded to topical imiquimod and had no relapse. We review the lit...

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Veröffentlicht in:The Pediatric infectious disease journal 2012-01, Vol.31 (1), p.97-100
Hauptverfasser: Hervás, Juan A, Martín-Santiago, Ana, Hervás, Daniel, Rojo, Estrella, Mena, Ana, Rocamora, Vicente, Dueñas, Joaquín
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container_end_page 100
container_issue 1
container_start_page 97
container_title The Pediatric infectious disease journal
container_volume 31
creator Hervás, Juan A
Martín-Santiago, Ana
Hervás, Daniel
Rojo, Estrella
Mena, Ana
Rocamora, Vicente
Dueñas, Joaquín
description We present a case of a child with Leishmania infantum cutaneous leishmaniasis unresponsive to 2 courses of intravenous liposomal amphotericin B, a treatment failure that has not been reported in this Leishmania species. The patient responded to topical imiquimod and had no relapse. We review the literature on the treatment failure of liposomal amphotericin B for cutaneous leishmaniasis.
doi_str_mv 10.1097/INF.0b013e31822dfbf7
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subjects Administration, Topical
Aminoquinolines - administration & dosage
Amphotericin B - administration & dosage
Animals
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antifungal agents
Antiparasitic agents
Antiprotozoal Agents - administration & dosage
Biological and medical sciences
Child
Human protozoal diseases
Humans
Infectious diseases
Leishmania infantum - drug effects
Leishmaniasis, Cutaneous - drug therapy
Leishmaniasis, Cutaneous - parasitology
Leshmaniasis
Liposomes - administration & dosage
Male
Medical sciences
Parasitic diseases
Pharmacology. Drug treatments
Protozoal diseases
Treatment Failure
Treatment Outcome
title Old World Leishmania infantum Cutaneous Leishmaniasis Unresponsive to Liposomal Amphotericin B Treated With Topical Imiquimod
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