Structures of Two New Phenolic Glycosides, Kaempferiaosides A and B, and Hepatoprotective Constituents from the Rhizomes of Kaempferia parviflora

Two new phenolic glycosides, kaempferiaosides A and B were isolated from the rhizomes of Kaempferia parviflora (Zingiberaceae) together with 24 known compounds. Their structures including absolute stereochemistry were elucidated on the basis of chemical and spectroscopic evidence. Among the isolates...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Chemical & pharmaceutical bulletin 2012/01/01, Vol.60(1), pp.62-69
Hauptverfasser:	Chaipech, Saowanee, Morikawa, Toshio, Ninomiya, Kiyofumi, Yoshikawa, Masayuki, Pongpiriyadacha, Yutana, Hayakawa, Takao, Muraoka, Osamu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cells, Cultured Glycosides - chemistry Glycosides - isolation & purification Glycosides - pharmacology Hepatocytes - drug effects hepatoprotective activity Kaempferia parviflora kaempferiaoside Krachai Dum Magnetic Resonance Spectroscopy Mice Molecular Conformation Phenols - chemistry Phenols - isolation & purification Phenols - pharmacology Protective Agents - chemistry Protective Agents - isolation & purification Protective Agents - pharmacology Rhizome - chemistry Zingiberaceae Zingiberaceae - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Two new phenolic glycosides, kaempferiaosides A and B were isolated from the rhizomes of Kaempferia parviflora (Zingiberaceae) together with 24 known compounds. Their structures including absolute stereochemistry were elucidated on the basis of chemical and spectroscopic evidence. Among the isolates, 5,3′-dihydroxy-3,7,4′-trimethoxyflavone showed higher activity than silybin, a commercial hepatoprotective agent.
ISSN:	0009-2363 1347-5223
DOI:	10.1248/cpb.60.62