Film materials with controlled release of biologically active substances

The properties of spun composites containing polyvinyl alcohol, a proteolytic enzyme (protease C or Terrilytin) and the high-molecular-weight antimicrobial polyhexamethyleneguanidine hydrochloride were investigated. The effect of the composition of the spinning compositions and spinning temperature on the properties of the film materials -- the activity, stability, and rate of release of biologically active substances -- was investigated. The possibility of obtaining polyvinyl alcohol films with controlled release of biologically active substances was demonstrated.[PUBLICATION ABSTRACT]