Multifunctional Mesoporous Composite Nanocapsules for Highly Efficient MRI-Guided High-Intensity Focused Ultrasound Cancer Surgery

Multifunctional Mesoporous Composite Nanocapsules for Highly Efficient MRI-Guided High-Intensity Focused Ultrasound Cancer Surgery

Bloodless surgical knife: Nano‐biotechnology has been introduced into imaging‐guided high‐intensity focused ultrasound (HIFU) cancer surgery by adopting engineered multifunctional manganese‐based mesoporous composite nanocapsules as the contrast agents for T1‐weighted magnetic resonance imaging (MRI...

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Veröffentlicht in:Angewandte Chemie International Edition 2011-12, Vol.50 (52), p.12505-12509
Hauptverfasser: Chen, Yu, Chen, Hangrong, Sun, Yang, Zheng, Yuanyi, Zeng, Deping, Li, Faqi, Zhang, Shengjian, Wang, Xia, Zhang, Kun, Ma, Ming, He, Qianjun, Zhang, Linlin, Shi, Jianlin
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Cancer
Contrast agents
Cutlery
high-intensity focused ultrasound
Humans
imaging agents
Liver Neoplasms - pathology
Liver Neoplasms - surgery
Liver Neoplasms - therapy
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
mesoporous materials
Nanocapsules - chemistry
Nanostructure
nanotechnology
Particle Size
Porosity
Rabbits
Surface Properties
Surgery
Ultrasonic Therapy
Ultrasound
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Zusammenfassung:Bloodless surgical knife: Nano‐biotechnology has been introduced into imaging‐guided high‐intensity focused ultrasound (HIFU) cancer surgery by adopting engineered multifunctional manganese‐based mesoporous composite nanocapsules as the contrast agents for T1‐weighted magnetic resonance imaging (MRI) and simultaneously as synergistic agents for MRI‐guided HIFU cancer surgery.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201106180