Determinants of Serum High Molecular Weight (HMW) Adiponectin Levels in Patients with Coronary Artery Disease: Associations with Cardio-renal-anemia Syndrome

Objective A low serum adiponectin level is associated with a high incidence of coronary artery disease (CAD) in the healthy population. Paradoxically, serum adiponectin is elevated in patients with severe CAD or chronic heart failure. We investigated the determinants of serum high molecular weight (...

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Veröffentlicht in:	Internal Medicine 2011, Vol.50(24), pp.2953-2960
Hauptverfasser:	Hara, Kenji, Uchida, Toshihiko, Takebayashi, Kohzo, Sakai, Yoshihiko, Inoue, Teruo, Inukai, Toshiko, Takayanagi, Kan, Aso, Yoshimasa
Format:	Artikel
Sprache:	eng
Schlagworte:	adiponectin Adiponectin - blood Adiponectin - chemistry Aged Anemia - blood Anemia - complications B-type natriuretic peptide Biomarkers - blood Biomarkers - chemistry Cardio-Renal Syndrome - blood Cardio-Renal Syndrome - complications chronic kidney disease coronary artery disease Coronary Artery Disease - blood Coronary Artery Disease - complications Female Humans Logistic Models Male metabolic syndrome Metabolic Syndrome - blood Metabolic Syndrome - complications Middle Aged Molecular Weight Natriuretic Peptide, Brain - blood Syndrome
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Zusammenfassung:	Objective A low serum adiponectin level is associated with a high incidence of coronary artery disease (CAD) in the healthy population. Paradoxically, serum adiponectin is elevated in patients with severe CAD or chronic heart failure. We investigated the determinants of serum high molecular weight (HMW) adiponectin in patients with CAD. Patients and Methods We studied 228 consecutive patients with CAD confirmed by angiography. Anemia was defined as a hemoglobin of
ISSN:	0918-2918 1349-7235
DOI:	10.2169/internalmedicine.50.5926