Transcatheter aortic valve implantation versus surgical aortic valve replacement: A propensity score analysis in patients at high surgical risk

Objectives Transcatheter aortic valve implantation (TAVI) has recently been advocated to decrease perioperative risk in high-risk patients. In this propensity-score analysis we compared outcomes after TAVI to those after surgical aortic valve replacement (AVR). Methods From June 2009 through June 20...

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Veröffentlicht in:The Journal of thoracic and cardiovascular surgery 2012, Vol.143 (1), p.64-71
Hauptverfasser: Conradi, Lenard, MD, Seiffert, Moritz, MD, Treede, Hendrik, MD, Silaschi, Miriam, Baldus, Stephan, MD, Schirmer, Johannes, MD, Kersten, Jan-Felix, Meinertz, Thomas, MD, Reichenspurner, Hermann, MD, PhD
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Sprache:eng
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Zusammenfassung:Objectives Transcatheter aortic valve implantation (TAVI) has recently been advocated to decrease perioperative risk in high-risk patients. In this propensity-score analysis we compared outcomes after TAVI to those after surgical aortic valve replacement (AVR). Methods From June 2009 through June 2010, 82 consecutive patients underwent TAVI via a transapical (n = 60) or transfemoral (n = 22) approach using the Edwards Sapien prosthesis (Edwards Lifesciences, Irvine, Calif). Mean patient age was 81.9 ± 5.2 years, 64.6% were women. Logistic EuroSCORE was 23.6% ± 1.4% and Society of Thoracic Surgeons score was 8.7% ± 1.3%. A group of 82 patients after surgical AVR was retrieved from our database, yielding a control group that was matched to the cases with respect to baseline demographics and typical risk factors. Results Overall mortality did not differ significantly between TAVI and AVR groups at 30 days (7.3% vs 8.6%), 90 days (13.6% vs 11.1%), or 180 days (17.8% vs 16.9%; P  = .889). Conversion to surgery was necessary in 2 (2.4%) TAVI cases. Perioperative stroke occurred in 2 (2.4%) cases per group. Pacemakers were implanted for new-onset heart block in 3.7% and 2.4% in the TAVI and AVR groups, respectively ( P  = 1.0). TAVI resulted in shorter operative times ( P  
ISSN:0022-5223
1097-685X
DOI:10.1016/j.jtcvs.2011.08.047