Development of Cystic Periventricular Leukomalacia in Newborn Infants after Rotavirus Infection

We describe 5 preterm and 3 term infants who presented with seizures during rotavirus infection within 6 weeks after birth. Six of these infants developed late-onset cystic periventricular leukomalacia. Four of the preterm infants had neurodevelopmental delay, and 4 (near) term infants had normal ea...

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Veröffentlicht in:	The Journal of pediatrics 2012, Vol.160 (1), p.165-168.e1
Hauptverfasser:	Verboon-Maciolek, Malgorzata A., MD, PhD, Truttmann, Anita C., MD, PhD, Groenendaal, Floris, MD, PhD, Skranes, Jon, MD, PhD, Døllner, Henrik, MD, PhD, Hunt, Rod W., BMBS, PhD, Hayman, Michael, MD, PhD, Dippersloot, Rob J., MD, PhD, van Loon, Anton M., MD, PhD, de Vries, Linda S., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Female General aspects Humans Infant, Newborn Infectious diseases Leukomalacia, Periventricular - virology Male Medical sciences neonates Neurology Pediatrics Rotavirus Rotavirus Infections - complications seizures Vascular diseases and vascular malformations of the nervous system Viral diseases
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Zusammenfassung:	We describe 5 preterm and 3 term infants who presented with seizures during rotavirus infection within 6 weeks after birth. Six of these infants developed late-onset cystic periventricular leukomalacia. Four of the preterm infants had neurodevelopmental delay, and 4 (near) term infants had normal early outcome.
ISSN:	0022-3476 1097-6833
DOI:	10.1016/j.jpeds.2011.08.053