Comparison of thromboelastometry (ROTEM®) with standard plasmatic coagulation testing in paediatric surgery
Thromboelastometry (ROTEM®) might be useful to detect intraoperative coagulation disorders early in major paediatric surgery. This observational trial compares this technique to standard coagulation tests. Intraoperative blood sampling was obtained in children undergoing elective major surgery. At e...
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Veröffentlicht in: | British journal of anaesthesia : BJA 2012-01, Vol.108 (1), p.36-41 |
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Sprache: | eng |
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Zusammenfassung: | Thromboelastometry (ROTEM®) might be useful to detect intraoperative coagulation disorders early in major paediatric surgery. This observational trial compares this technique to standard coagulation tests.
Intraoperative blood sampling was obtained in children undergoing elective major surgery. At each time point, standard coagulation tests [activated partial thromboplastin time (aPTT), prothrombin time (PT), and fibrinogen level] and ROTEM® analyses (InTEM, ExTEM, and FibTEM) were performed simultaneously by trained hospital laboratory staff.
A total of 288 blood samples from 50 subjects were analysed. While there was a poor correlation between PT and aPTT to ExTEM clotting time (CT) and InTEM CT, respectively, a good correlation was detected between PT and aPTT to clot formation time, and a very good correlation between fibrinogen level and FibTEM assay (r=0.882, P |
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ISSN: | 0007-0912 1471-6771 |
DOI: | 10.1093/bja/aer342 |