Recurrence of macular edema in retinal vein occlusions after treatment with intravitreal ranibizumab (Lucentis)

Abstract Objective To evaluate the recurrence of macular edema (ME) in a mixed group of patients with branch (BRVO) and central (CRVO) retinal vein occlusion after early onset treatment with intravitreal injections of ranibizumab. Design Nonrandomized, uncontrolled prospective clinical trial. Participants Forty patients were enrolled in our study. Twenty-two patients had BRVO and 18 patients had CRVO. Methods All patients had a minimum follow-up of 12 months. All patients had fundus fluorescein angiography (FFA) and optical coherence tomography (OCT) at presentation. The time period between RVO occurrences and initial examination and treatment was