European neuroborreliosis: quality of life 30months after treatment

Eikeland R, Mygland Aa, Herlofson K, Ljoestad U. European neuroborreliosis: quality of life 30months after treatment. Acta Neurol Scand: 2011: 124: 349-354. [copy 2011 John Wiley & Sons A/S. Objectives- The prognosis after Lyme neuroborreliosis (LNB) is debated. The aim of this study was to assess health-related Quality of Life (QoL) and neurological symptoms 30months after treatment in European patients with LNB. Materials and methods- In a prospective case-control designed study, we investigated 50 well-characterized patients with LNB who had participated in a treatment trial for LNB 30months earlier and 50 matched control persons with the health QoL questionnaire Short-Form 36 (SF-36), the Fatigue Severity Scale (FSS), the Montgomery and Aasberg Depression Rating Scale (MADRS), the Starkstein Apathy Scale (SAS), and the Mini Mental State (MMS). Clinical and demographic data were collected by semi-structured interviews and clinical neurological examination. Results- Lyme neuroborreliosis-treated patients scored lower than control persons in the SF-36 domains physical component summary (PCS) (44 vs 51 P