Evidence for differing evolutionary dynamics of A/H5N1 viruses among countries applying or not applying avian influenza vaccination in poultry

Highlights ► Phylogenetic and evolutionary analysis of Egyptian H5N1 viruses was undertaken. ► Evolution of H5N1 in countries applying or not vaccination was compared. ► Distinct Egyptian H5N1 subclades have co-circulated in poultry since late 2007. ► Evolutionary rates were different among countrie...

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Veröffentlicht in:Vaccine 2011-11, Vol.29 (50), p.9368-9375
Hauptverfasser: Cattoli, Giovanni, Fusaro, Alice, Monne, Isabella, Coven, Fethiye, Joannis, Tony, El-Hamid, Hatem S. Abd, Hussein, Aly Ahmed, Cornelius, Claire, Amarin, Nadim Mukhles, Mancin, Marzia, Holmes, Edward C, Capua, Ilaria
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Sprache:eng
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Zusammenfassung:Highlights ► Phylogenetic and evolutionary analysis of Egyptian H5N1 viruses was undertaken. ► Evolution of H5N1 in countries applying or not vaccination was compared. ► Distinct Egyptian H5N1 subclades have co-circulated in poultry since late 2007. ► Evolutionary rates were different among countries applying or not vaccination.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2011.09.127