Alterations in Red Blood Cell Volume and Hemoglobin Concentration, Viscoelastic Properties, and Mechanical Fragility Caused by Continuous Flow Pumping in Calves

In this study, we have analyzed the changes in mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), and the dynamic deformability and mechanical fragility of red blood cells (RBCs) in five male Holstein calves (body weight: 95.6 ± 10.8 kg) whose circulation was partially...

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Veröffentlicht in:Artificial organs 2011-08, Vol.35 (8), p.791-799
Hauptverfasser: Yokoyama, Naoyuki, Sakota, Daisuke, Nagaoka, Eiki, Takatani, Setsuo
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Sprache:eng
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Zusammenfassung:In this study, we have analyzed the changes in mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), and the dynamic deformability and mechanical fragility of red blood cells (RBCs) in five male Holstein calves (body weight: 95.6 ± 10.8 kg) whose circulation was partially supported with a novel magnetically levitated extracorporeal centrifugal blood pump MedTech Dispo. One hour after the pumping has started, the MCV increased and the MCHC decreased by 1.064 ± 0.006 and 0.906 ± 0.050 times, respectively, as compared with those of the prepumped blood (P 
ISSN:0160-564X
1525-1594
DOI:10.1111/j.1525-1594.2011.01317.x