Should veterinarians consider acrylamide that potentially occurs in starch-rich foodstuffs as a neurotoxin in dogs?

Three clinically healthy Labrador puppies developed ataxia, hypermetria and convulsions shortly after eating the burnt crust of maize porridge. Two of the puppies died. Acrylamide toxicity was considered based on the history of all 3 puppies developing nervous signs after being exposed to a starch-b...

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Veröffentlicht in:Journal of the South African Veterinary Association 2011-06, Vol.82 (2), p.129-130
Hauptverfasser: Le Roux-Pullen, L, Lessing, D
Format: Artikel
Sprache:eng
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Zusammenfassung:Three clinically healthy Labrador puppies developed ataxia, hypermetria and convulsions shortly after eating the burnt crust of maize porridge. Two of the puppies died. Acrylamide toxicity was considered based on the history of all 3 puppies developing nervous signs after being exposed to a starch-based foodstuff that was subjected to high temperature during preparation. Acrylamide-induced neurotoxicity is thought to partially result from a distal axonopathy.
ISSN:1019-9128
2224-9435
DOI:10.4102/jsava.v82i2.47