A comparative study of interfaces for microchip micellar electrokinetic chromatography-electrospray ionization mass spectrometry using the surfactant ammonium dodecyl sulfate

Using ammonium dodecyl sulfate (ADS) as the surfactant, the response of three common interfaces in the direct coupling of microchip micellar electrokinetic chromatography with electrospray ionization mass spectrometry was studied. In the range of 10–40 mM surfactant, a conventional sheath liquid int...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Electrophoresis 2011-11, Vol.32 (23), p.3385-3391
Hauptverfasser:	Huang, Ju-Li, Li, Fu-An, Her, Guor-Rong
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - analysis Chromatography, Micellar Electrokinetic Capillary - instrumentation Chromatography, Micellar Electrokinetic Capillary - methods Limit of Detection Low sheath flow interface Microchip MEKC/MS Microfluidic Analytical Techniques - instrumentation Models, Chemical PMMA microchip Polymethyl Methacrylate - chemistry Reproducibility of Results Sheath liquid interface Sheathless interface Sodium Dodecyl Sulfate - chemistry Spectrometry, Mass, Electrospray Ionization - methods Sulfonamides - analysis Surface-Active Agents - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Using ammonium dodecyl sulfate (ADS) as the surfactant, the response of three common interfaces in the direct coupling of microchip micellar electrokinetic chromatography with electrospray ionization mass spectrometry was studied. In the range of 10–40 mM surfactant, a conventional sheath liquid interface provided poorer sensitivity than both sheathless interface and low‐sheath‐flow interface. At a surfactant concentration
ISSN:	0173-0835 1522-2683
DOI:	10.1002/elps.201100288