Risk factors for bacteraemia attributable to Pseudomonas aeruginosa resistant to imipenem, levofloxacin, or gentamicin

Summary We studied the risk factors associated with resistance to imipenem, levofloxacin and gentamicin in Pseudomonas aeruginosa isolated from blood cultures of 175 patients in a hospital in Japan. Imipenem resistance was associated with transfer from another hospital, and receiving antifungal medi...

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Veröffentlicht in:	The Journal of hospital infection 2011-11, Vol.79 (3), p.267-268
Hauptverfasser:	Mikura, S, Wada, H, Okazaki, M, Nakamura, M, Honda, K, Yasutake, T, Higaki, M, Ishii, H, Watanabe, T, Tsunoda, T, Goto, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Anti-Bacterial Agents - pharmacology Antibacterial agents Antibiotic resistance Antibiotics. Antiinfectious agents. Antiparasitic agents Bacteremia - microbiology Bacterial diseases Bacterial sepsis Biological and medical sciences Child Child, Preschool Drug Resistance, Multiple, Bacterial Female Gentamicin Gentamicins - pharmacology Gentamicins - therapeutic use Human bacterial diseases Humans Imipenem Imipenem - pharmacology Imipenem - therapeutic use Infant Infant, Newborn Infectious Disease Infectious diseases Levofloxacin Male Medical sciences Middle Aged Ofloxacin - pharmacology Ofloxacin - therapeutic use Pharmacology. Drug treatments Pseudomonas aeruginosa Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - isolation & purification Pseudomonas Infections - microbiology Risk Factors Young Adult
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Zusammenfassung:	Summary We studied the risk factors associated with resistance to imipenem, levofloxacin and gentamicin in Pseudomonas aeruginosa isolated from blood cultures of 175 patients in a hospital in Japan. Imipenem resistance was associated with transfer from another hospital, and receiving antifungal medication. Gentamicin resistance was associated with previous administration of a penicillin. No specific risk factors were associated with levofloxacin resistance.
ISSN:	0195-6701 1532-2939
DOI:	10.1016/j.jhin.2011.07.003