Simultaneous electrochemical detection of both PSMA (+) and PSMA (-) prostate cancer cells using an RNA/peptide dual-aptamer probe

Using an RNA/peptide dual-aptamer probe, both PSMA (+) and PSMA (-) prostate cancer cells were simultaneously detected by electrochemical impedance spectroscopy. This approach can be applied as a general tool for early diagnosis of prostate cancer.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2010-08, Vol.46 (30), p.5566-5568
Hauptverfasser: Min, Kyoungin, Song, Kyung-Mi, Cho, Minseon, Chun, Yang-Sook, Shim, Yoon-Bo, Ku, Ja Kang, Ban, Changill
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container_end_page 5568
container_issue 30
container_start_page 5566
container_title Chemical communications (Cambridge, England)
container_volume 46
creator Min, Kyoungin
Song, Kyung-Mi
Cho, Minseon
Chun, Yang-Sook
Shim, Yoon-Bo
Ku, Ja Kang
Ban, Changill
description Using an RNA/peptide dual-aptamer probe, both PSMA (+) and PSMA (-) prostate cancer cells were simultaneously detected by electrochemical impedance spectroscopy. This approach can be applied as a general tool for early diagnosis of prostate cancer.
doi_str_mv 10.1039/c002524k
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source MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Amino Acid Sequence
Antigens, Surface - analysis
Aptamers, Nucleotide - chemistry
Aptamers, Peptide - chemistry
Base Sequence
Cell Line, Tumor
Glutamate Carboxypeptidase II - analysis
Humans
Male
Molecular Sequence Data
Prostatic Neoplasms - diagnosis
Sensitivity and Specificity
title Simultaneous electrochemical detection of both PSMA (+) and PSMA (-) prostate cancer cells using an RNA/peptide dual-aptamer probe
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