Simultaneous electrochemical detection of both PSMA (+) and PSMA (-) prostate cancer cells using an RNA/peptide dual-aptamer probe

Using an RNA/peptide dual-aptamer probe, both PSMA (+) and PSMA (-) prostate cancer cells were simultaneously detected by electrochemical impedance spectroscopy. This approach can be applied as a general tool for early diagnosis of prostate cancer.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2010-08, Vol.46 (30), p.5566-5568
Hauptverfasser:	Min, Kyoungin, Song, Kyung-Mi, Cho, Minseon, Chun, Yang-Sook, Shim, Yoon-Bo, Ku, Ja Kang, Ban, Changill
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Antigens, Surface - analysis Aptamers, Nucleotide - chemistry Aptamers, Peptide - chemistry Base Sequence Cell Line, Tumor Glutamate Carboxypeptidase II - analysis Humans Male Molecular Sequence Data Prostatic Neoplasms - diagnosis Sensitivity and Specificity
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Beschreibung
Zusammenfassung:	Using an RNA/peptide dual-aptamer probe, both PSMA (+) and PSMA (-) prostate cancer cells were simultaneously detected by electrochemical impedance spectroscopy. This approach can be applied as a general tool for early diagnosis of prostate cancer.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c002524k