DNA-mediated site-specific deposition of gold nanoparticles on silicon wafers

We report a method for the site-specific deposition of gold nanoparticles, as programmed by DNA sequences immobilized on the surface of silicon oxide-coated silicon wafers. After optimization of surface chemistries, selectivities of between 8:1 and 118:1 were achieved for the DNA-based sorting of po...

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Veröffentlicht in:Nanoscale 2010-12, Vol.2 (12), p.2579-2582
Hauptverfasser: Heimann, Katharina J C, Richert, Clemens
Format: Artikel
Sprache:eng
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Zusammenfassung:We report a method for the site-specific deposition of gold nanoparticles, as programmed by DNA sequences immobilized on the surface of silicon oxide-coated silicon wafers. After optimization of surface chemistries, selectivities of between 8:1 and 118:1 were achieved for the DNA-based sorting of populations of gold nanoparticle of 15 nm and 60 nm diameter from a common suspension via oligonucleotide duplex formation.
ISSN:2040-3364
2040-3372
DOI:10.1039/c0nr00612b