Deoxyribonucleic Acid Molecular Design for Electrochemical Biosensors

A new electrochemical biosensors based on the DNA configuration switch was represented in this review. Special DNA probes (stem-loop or aptamers etc.) on the electrode surface dramatically change their configuration on the combination of target molecular giving birth to a detectable electrochemical...

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Veröffentlicht in:Fēnxī huàxué 2011-07, Vol.39 (7), p.953-962
Hauptverfasser: Liu, Gang, Wan, Ying, Zou, Zi-Ying, Ren, Shu-Zhen, Fan, Chun-Hai
Format: Artikel
Sprache:chi ; eng
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Zusammenfassung:A new electrochemical biosensors based on the DNA configuration switch was represented in this review. Special DNA probes (stem-loop or aptamers etc.) on the electrode surface dramatically change their configuration on the combination of target molecular giving birth to a detectable electrochemical signal. This strategy attracts extensive research interesting for its easier operation and less unspecific absorption, To this day, its analysis performance has been markedly developed with an expanding application. Here, we summarize the history of these sensors.
ISSN:0253-3820
DOI:10.3724/SP.J.1096.2011.00953