p53 binding protein 1 foci as a biomarker of DNA double strand breaks induced by ionizing radiation

Foci of p53 binding protein 1 (53 BP1) have been used as a biomarker of DNA double-strand breaks (DSBs) in cells induced by ionizing radiations. 53 BP1 was shown to relocalize into foci shortly after irradiation, with the number of foci closely paralleling the number of DNA DSBs. However, consensus...

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Veröffentlicht in:	Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment Accelerators, spectrometers, detectors and associated equipment, 2011-12, Vol.660 (1), p.116-120
Hauptverfasser:	Ng, C.K.M., Wong, M.Y.P., Lam, R.K.K., Ho, J.P.Y., Chiu, S.K., Yu, K.N.
Format:	Artikel
Sprache:	eng
Schlagworte:	53 BP1 Alpha particle Bysta effect DNA Radiation effect
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