Use of Interferon-Gamma Release Assay for Latent Tuberculosis Infection Screening in Older Adults Exposed to Tuberculosis in a Nursing Home

OBJECTIVES: To assess the additive value of a newly marketed interferon‐gamma release assay, QuantiFERON‐TB Gold In‐Tube (QFT‐GIT), to a single tuberculin skin test (TST) for the detection of latent tuberculosis infection (LTBI) in older adults who have been exposed to TB in a nursing home. DESIGN:...

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Veröffentlicht in:	Journal of the American Geriatrics Society (JAGS) 2011-05, Vol.59 (5), p.858-862
Hauptverfasser:	Katsenos, Stamatis, Nikolopoulou, Melita, Gartzonika, Constantina, Manda-Stachouli, Carmen, Gogali, Athena, Grypaiou, Christodoula, Mavridis, Anestis, Constantopoulos, Stavros H., Daskalopoulos, George
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged, 80 and over Anergy Bacterial diseases Biological and medical sciences Chest Contact tracing Cross Infection - diagnosis elderly Female gamma -Interferon General aspects Geriatrics Gold Human bacterial diseases Human exposure Humans Infection Infectious diseases Interferon-gamma Latent Tuberculosis - diagnosis latent tuberculosis infection Male Mass Screening - methods Medical sciences Medical screening Mycobacterium Nursing Nursing Homes Older people Prevention and actions Public health. Hygiene Public health. Hygiene-occupational medicine QuantiFERON-TB Gold In-Tube Radiography Skin tests Tuberculin tuberculin skin test Tuberculin Test - methods Tuberculosis Tuberculosis and atypical mycobacterial infections
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Beschreibung
Zusammenfassung:	OBJECTIVES: To assess the additive value of a newly marketed interferon‐gamma release assay, QuantiFERON‐TB Gold In‐Tube (QFT‐GIT), to a single tuberculin skin test (TST) for the detection of latent tuberculosis infection (LTBI) in older adults who have been exposed to TB in a nursing home. DESIGN: Contact tracing included clinical examination, chest radiography, TST, and QFT‐GIT in TST‐negative people (TST
ISSN:	0002-8614 1532-5415
DOI:	10.1111/j.1532-5415.2011.03367.x