Production of hyaluronic acid from Streptococcus zooepidemicus MTCC 3523 and its wound healing activity

Exopolysaccharide produced and purified from Streptococcus zooepidemicus MTCC 3523 was identified as hyaluronic acid (HA) based on IR and NMR spectroscopy while its Mw was found to be 5.38 × 10 5 Da. HA produced passed bacterial endotoxin test and showed significant wound healing activity in Wistar...

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Veröffentlicht in:	Journal of bioscience and bioengineering 2011-03, Vol.111 (3), p.286-288
Hauptverfasser:	Patil, Kanchankumar P., Patil, Deepak K., Chaudhari, Bhushan L., Chincholkar, Sudhir B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biotechnology Culture Media Fermentation Fundamental and applied biological sciences. Psychology Hyaluronic acid Hyaluronic Acid - biosynthesis Hyaluronic Acid - pharmacology Rats Rats, Wistar Streptococcus Streptococcus equi - metabolism Streptococcus equi subsp. zooepidemicus MTCC 3523 Wound Healing Wound healing activity
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Beschreibung
Zusammenfassung:	Exopolysaccharide produced and purified from Streptococcus zooepidemicus MTCC 3523 was identified as hyaluronic acid (HA) based on IR and NMR spectroscopy while its Mw was found to be 5.38 × 10 5 Da. HA produced passed bacterial endotoxin test and showed significant wound healing activity in Wistar rats on 12th and 16th day.
ISSN:	1389-1723 1347-4421
DOI:	10.1016/j.jbiosc.2010.10.012