Catalytic Hydroacylation as an Approach to Homoaldol Products
A method has been developed for the intermolecular hydroacylation of homoallyl alcohols with salicylaldehydes to furnish homoaldol products in 50–98% yields. The method also applies to the hydroacylation of 2-hydroxystyrenes. This work highlights the use of hydroacylation as a unified approach to bo...
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| Veröffentlicht in: | Organic letters 2011-12, Vol.13 (23), p.6216-6219 |
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| container_issue | 23 |
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| container_title | Organic letters |
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| creator | Murphy, Stephen K Petrone, David A Coulter, Matthew M Dong, Vy M |
| description | A method has been developed for the intermolecular hydroacylation of homoallyl alcohols with salicylaldehydes to furnish homoaldol products in 50–98% yields. The method also applies to the hydroacylation of 2-hydroxystyrenes. This work highlights the use of hydroacylation as a unified approach to both aldol and homoaldol products. |
| doi_str_mv | 10.1021/ol202663p |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1523-7060 |
| ispartof | Organic letters, 2011-12, Vol.13 (23), p.6216-6219 |
| issn | 1523-7060 1523-7052 |
| language | eng |
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| source | MEDLINE; American Chemical Society Journals |
| subjects | Alcohols - chemical synthesis Alcohols - chemistry Aldehydes - chemical synthesis Aldehydes - chemistry Catalysis Combinatorial Chemistry Techniques Styrenes - chemistry |
| title | Catalytic Hydroacylation as an Approach to Homoaldol Products |
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