Plasmonically active micron-sized beads for integrated solid-phase synthesis and label-free SERS analysis

Self-assembly of gold nanospheres with a very thin glass shell onto the surface of beads yields a plasmonically active micron-sized substrate for integrated solid-phase synthesis and label-free SERS analysis. The proof-of-principle of this approach is demonstrated by the vibrational spectroscopic di...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2011-12, Vol.47 (48), p.12762-12764
Hauptverfasser:	Gellner, Magdalena, Niebling, Stephan, Kuchelmeister, Hannes Y, Schmuck, Carsten, Schlücker, Sebastian
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Amino Acids - chemistry Beads Dipeptides - chemistry Discrimination Gold - chemistry Metal Nanoparticles - chemistry Nanospheres Nanostructures - chemistry Particle Size Self assembly Shells Silicon Dioxide - chemistry Solid-Phase Synthesis Techniques Spectrum Analysis, Raman Surface chemistry Synthesis
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Beschreibung
Zusammenfassung:	Self-assembly of gold nanospheres with a very thin glass shell onto the surface of beads yields a plasmonically active micron-sized substrate for integrated solid-phase synthesis and label-free SERS analysis. The proof-of-principle of this approach is demonstrated by the vibrational spectroscopic discrimination of three distinct amino acids and a dipeptide.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c1cc13562g