Just add tetrazole: 5-(2-pyrrolo)tetrazoles are simple, highly potent anion recognition elements

We report a novel pyrrolo-tetrazole motif that encodes anion binding orders of magnitude stronger than closely related systems and suggests the general utility of amide-tetrazole exchanges for creating simple, high-affinity anion binders.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2011-12, Vol.47 (47), p.12688-12690
Hauptverfasser: Courtemanche, Rebecca J M, Pinter, Thomas, Hof, Fraser
Format: Artikel
Sprache:eng
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Zusammenfassung:We report a novel pyrrolo-tetrazole motif that encodes anion binding orders of magnitude stronger than closely related systems and suggests the general utility of amide-tetrazole exchanges for creating simple, high-affinity anion binders.
ISSN:1359-7345
1364-548X
DOI:10.1039/c1cc15875a