Forme fruste anterior segment dysgenesis
[...]these ocular entities were described by Peters and Axenfeld, the embryologic origin of the affected tissues was not known. 1 2 However, Johnston's avian experiments revealed that the corneal endothelium, stroma, and trabecular meshwork are all derived from migrating neural crest cells and...
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Veröffentlicht in: | British journal of ophthalmology 2011-12, Vol.95 (12), p.1756-1757 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | [...]these ocular entities were described by Peters and Axenfeld, the embryologic origin of the affected tissues was not known. 1 2 However, Johnston's avian experiments revealed that the corneal endothelium, stroma, and trabecular meshwork are all derived from migrating neural crest cells and referred to as anterior segment dysgenesis. 3 The genetic inheritance of Peters' anomaly is usually sporadic, but several genetic mutations have been reported in literature. [...]we assert that this case illustrates the importance of considering the diseases of anterior segment dysgenesis as a spectrum of findings and conditions and not as distinct entities. |
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ISSN: | 0007-1161 1468-2079 |
DOI: | 10.1136/bjo.2009.177535 |