Forme fruste anterior segment dysgenesis

[...]these ocular entities were described by Peters and Axenfeld, the embryologic origin of the affected tissues was not known. 1 2 However, Johnston's avian experiments revealed that the corneal endothelium, stroma, and trabecular meshwork are all derived from migrating neural crest cells and...

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Veröffentlicht in:British journal of ophthalmology 2011-12, Vol.95 (12), p.1756-1757
Hauptverfasser: Banitt, M R, Romano, A, Iragavarapu, S, Budenz, D L, Lee, R K
Format: Artikel
Sprache:eng
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Zusammenfassung:[...]these ocular entities were described by Peters and Axenfeld, the embryologic origin of the affected tissues was not known. 1 2 However, Johnston's avian experiments revealed that the corneal endothelium, stroma, and trabecular meshwork are all derived from migrating neural crest cells and referred to as anterior segment dysgenesis. 3 The genetic inheritance of Peters' anomaly is usually sporadic, but several genetic mutations have been reported in literature. [...]we assert that this case illustrates the importance of considering the diseases of anterior segment dysgenesis as a spectrum of findings and conditions and not as distinct entities.
ISSN:0007-1161
1468-2079
DOI:10.1136/bjo.2009.177535