The effect of honey-coated bandages compared with silver-coated bandages on treatment of malignant wounds-a randomized study

Malignant wounds (MWs) occur in 5–10% of all cancer patients. Malodor and exudation are the most common side effects. The aim was to determine the influence of honey‐coated compared with silver‐coated bandages on treatment of MWs. Patients were randomly selected to enter either group A (honey‐coated...

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Veröffentlicht in:Wound repair and regeneration 2011-11, Vol.19 (6), p.664-670
Hauptverfasser: Lund-Nielsen, Betina, Adamsen, Lis, Kolmos, Hans Jørn, Rørth, Mikael, Tolver, Anders, Gottrup, Finn
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Sprache:eng
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Zusammenfassung:Malignant wounds (MWs) occur in 5–10% of all cancer patients. Malodor and exudation are the most common side effects. The aim was to determine the influence of honey‐coated compared with silver‐coated bandages on treatment of MWs. Patients were randomly selected to enter either group A (honey‐coated bandages) or group B (silver‐coated bandages). Parameters were the following: wound size, cleanliness, malodor, exudation, and wound pain. Digital photographs, visual analog scales (VAS), and wound morphology registration were used for measurement at baseline and following the 4‐week intervention. Sixty‐nine patients with MWs and advanced cancer, aged 47–90 (median 65.6), were included. No statistically significant difference was noted between the groups with respect to wound size, degree of cleanliness, exudation, malodor, and wound pain. There was a median decrease in wound size of 15 cm2 and 8 cm2 in group A and B, respectively (p = 0.63). Based on post‐intervention pooled data from the groups, improvement was seen in 62% of the participants with respect to wound size and in 58% (n = 69) with respect to cleanliness. The VAS score for malodor (p = 0.007) and exudation (p 
ISSN:1067-1927
1524-475X
DOI:10.1111/j.1524-475X.2011.00735.x