Synthesis and antimicrobial activity of methyl esters of 2-(het)arylamino-4-oxo-Z-2-butenoic acids, their structural analogs, and conversion products

Synthesis and antimicrobial activity of methyl esters of 2-(het)arylamino-4-oxo-Z-2-butenoic acids, their structural analogs, and conversion products

Synthesis of a small library of compounds containing an aminovinylketone fragment is described. Results of studying their antibacterial activity against S. aureus ATCC 6538-P and E. coli ATCC 25922 are reported.

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Veröffentlicht in:Pharmaceutical chemistry journal 2008-08, Vol.42 (8), p.452-455
Hauptverfasser: Boteva, A. A., Krasnykh, O. P., Dubrovina, S. S., Vakhrin, M. I., Babushkina, E. B., Odegova, T. F., Solova, I. V.
Format: Artikel
Sprache:eng
Schlagworte:
Escherichia coli
Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
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Zusammenfassung:Synthesis of a small library of compounds containing an aminovinylketone fragment is described. Results of studying their antibacterial activity against S. aureus ATCC 6538-P and E. coli ATCC 25922 are reported.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-008-0160-4