Active cyamemazine metabolites in patients treated with cyamemazine (Tercian registered ): influence on cerebral dopamine D sub(2) and serotonin 5-HT sub(2A) receptor occupancy as measured by positron emission tomography (PET)
Rationale: Cyamemazine (Tercian registered ) is an antipsychotic agent blocking central dopamine D sub(2) receptors, which induces few extrapyramidal adverse effects, due to a potent antagonistic action at serotonin 5-HT sub(2A) receptors. In vitro studies showed that the desmethyl metabolite of cya...
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| Veröffentlicht in: | Psychopharmacology 2011-10, Vol.217 (3), p.315-321 |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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