Helicase Multitasking in Ribosome Assembly

In this issue of Molecular Cell, Bohnsack et al. (2009) identify multiple binding sites of the RNA helicase Prp43 on preribosomal RNA. The target regions suggest distinct functions of Prp43 in ribosome biogenesis.

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Bibliographische Detailangaben
Veröffentlicht in:	Molecular cell 2009-11, Vol.36 (4), p.537-538
Hauptverfasser:	Guenther, Ulf-Peter, Jankowsky, Eckhard
Format:	Artikel
Sprache:	eng
Schlagworte:	DEAD-box RNA Helicases - deficiency DEAD-box RNA Helicases - metabolism DNA helicase Models, Biological Protein Binding Ribosomes - metabolism RNA Precursors - metabolism RNA, Fungal - chemistry RNA, Fungal - genetics RNA, Ribosomal - metabolism Saccharomyces cerevisiae - enzymology Saccharomyces cerevisiae Proteins - metabolism
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Beschreibung
Zusammenfassung:	In this issue of Molecular Cell, Bohnsack et al. (2009) identify multiple binding sites of the RNA helicase Prp43 on preribosomal RNA. The target regions suggest distinct functions of Prp43 in ribosome biogenesis.
ISSN:	1097-2765 1097-4164
DOI:	10.1016/j.molcel.2009.11.004