Endogenous Ocular Nocardiosis—An Interventional Case Report With a Review of the Literature

Abstract We present an illustrative case of endogenous ocular Nocardia (EON) infection in a man with Hodgkin disease treated by chemotherapy who underwent aggressive vitreoretinal surgery for diagnosis and treatment of a subretinal abscess. Visual acuity recovered from hand movements to 20/25. We re...

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Veröffentlicht in:	Survey of ophthalmology 2011-09, Vol.56 (5), p.383-415
Hauptverfasser:	Eschle-Meniconi, Margherita E., MD, Guex-Crosier, Yan, MD, Wolfensberger, Thomas J., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Abscess - diagnosis Abscess - drug therapy Abscess - microbiology Aged amikacin Bacterial diseases Biological and medical sciences chorioretinal exudates chorioretinitis endogenous ocular Nocardia infection endophthalmitis Eye Infections, Bacterial - diagnosis Eye Infections, Bacterial - drug therapy Eye Infections, Bacterial - microbiology Fatal Outcome Human bacterial diseases Humans hypopyon Infectious diseases Male Medical sciences Microbial Sensitivity Tests Miscellaneous Nocardia Nocardia - isolation & purification Nocardia Infections - diagnosis Nocardia Infections - drug therapy Nocardia Infections - microbiology nocardiosis Ophthalmology resistance Retinal Diseases - diagnosis Retinal Diseases - drug therapy Retinal Diseases - microbiology Retinopathies subretinal abscess Trimethoprim, Sulfamethoxazole Drug Combination - therapeutic use trimethoprim-sulfamethoxazole Uvea diseases uveitis
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Zusammenfassung:	Abstract We present an illustrative case of endogenous ocular Nocardia (EON) infection in a man with Hodgkin disease treated by chemotherapy who underwent aggressive vitreoretinal surgery for diagnosis and treatment of a subretinal abscess. Visual acuity recovered from hand movements to 20/25. We review the 38 reported cases of EON published between 1967 and 2007, describe the clinical presentation from a systemic and ocular point of view, examine which ocular procedures were successful in identifying the bacterium, and analyze ocular morbidity and the factors affecting successful treatment.
ISSN:	0039-6257 1879-3304
DOI:	10.1016/j.survophthal.2011.03.003