PET kinetic analysis--compartmental model

PET enables not only visualization of the distribution of radiotracer, but also has ability to quantify several biomedical functions. Compartmental model is a basic idea to analyze dynamic PET data. This review describes the principle of the compartmental model and categorizes the techniques and app...

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Veröffentlicht in:Annals of nuclear medicine 2006-11, Vol.20 (9), p.583-588
Hauptverfasser: Watabe, Hiroshi, Ikoma, Yoko, Kimura, Yuichi, Naganawa, Mika, Shidahara, Miho
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container_end_page 588
container_issue 9
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container_title Annals of nuclear medicine
container_volume 20
creator Watabe, Hiroshi
Ikoma, Yoko
Kimura, Yuichi
Naganawa, Mika
Shidahara, Miho
description PET enables not only visualization of the distribution of radiotracer, but also has ability to quantify several biomedical functions. Compartmental model is a basic idea to analyze dynamic PET data. This review describes the principle of the compartmental model and categorizes the techniques and approaches for the compartmental model according to various aspects: model design, experimental design, invasiveness, and mathematical solution. We also discussed advanced applications of the compartmental analysis with PET.
doi_str_mv 10.1007/BF02984655
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subjects Computer Simulation
Data Interpretation, Statistical
Fluorodeoxyglucose F18 - pharmacokinetics
Humans
Kinetics
Magnetic Resonance Imaging
Models, Theoretical
Neoplasm Staging
Positron-Emission Tomography - instrumentation
Positron-Emission Tomography - methods
Radioisotopes - pharmacokinetics
Telencephalon - pathology
Tomography, Emission-Computed, Single-Photon - methods
title PET kinetic analysis--compartmental model
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