PET kinetic analysis--compartmental model

PET enables not only visualization of the distribution of radiotracer, but also has ability to quantify several biomedical functions. Compartmental model is a basic idea to analyze dynamic PET data. This review describes the principle of the compartmental model and categorizes the techniques and app...

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Veröffentlicht in:	Annals of nuclear medicine 2006-11, Vol.20 (9), p.583-588
Hauptverfasser:	Watabe, Hiroshi, Ikoma, Yoko, Kimura, Yuichi, Naganawa, Mika, Shidahara, Miho
Format:	Artikel
Sprache:	eng
Schlagworte:	Computer Simulation Data Interpretation, Statistical Fluorodeoxyglucose F18 - pharmacokinetics Humans Kinetics Magnetic Resonance Imaging Models, Theoretical Neoplasm Staging Positron-Emission Tomography - instrumentation Positron-Emission Tomography - methods Radioisotopes - pharmacokinetics Telencephalon - pathology Tomography, Emission-Computed, Single-Photon - methods
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Beschreibung
Zusammenfassung:	PET enables not only visualization of the distribution of radiotracer, but also has ability to quantify several biomedical functions. Compartmental model is a basic idea to analyze dynamic PET data. This review describes the principle of the compartmental model and categorizes the techniques and approaches for the compartmental model according to various aspects: model design, experimental design, invasiveness, and mathematical solution. We also discussed advanced applications of the compartmental analysis with PET.
ISSN:	0914-7187 1864-6433
DOI:	10.1007/BF02984655