Regional cerebral blood flow in a patient with Nasu-Hakola disease

We report a functional neuroimaging study of a 43-year-old woman with Nasu-Hakola disease (NHD). Regional cerebral blood flow (rCBF) images were measured with technetium-99m ethyl cysteinate dimer single photon emission computed tomography (SPECT). rCBF was decreased in the bilateral frontal lobes a...

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Veröffentlicht in:	Annals of nuclear medicine 2005-06, Vol.19 (4), p.309-312
Hauptverfasser:	Takeshita, Tohru, Kaminaga, Tatsuro, Tatsumi, Tomoko, Hatanaka, Yuki, Furui, Shigeru
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Blood flow Brain Brain - blood supply Brain - diagnostic imaging Cerebral blood flow Cerebrovascular Circulation Chromosome Disorders - diagnostic imaging Computed tomography Cysteine - analogs & derivatives Dementia, Vascular - diagnostic imaging Female Humans Lipodystrophy - congenital Lipodystrophy - diagnostic imaging Medical imaging Memory Disorders - diagnostic imaging Nasu-Hakola disease Neuroimaging Organotechnetium Compounds Osteochondrodysplasias - congenital Osteochondrodysplasias - diagnostic imaging Photon emission Radionuclide Imaging Radiopharmaceuticals Single photon emission computed tomography Syndrome Technetium Technetium isotopes Thalamus
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Zusammenfassung:	We report a functional neuroimaging study of a 43-year-old woman with Nasu-Hakola disease (NHD). Regional cerebral blood flow (rCBF) images were measured with technetium-99m ethyl cysteinate dimer single photon emission computed tomography (SPECT). rCBF was decreased in the bilateral frontal lobes and thalamus. This finding was consistent with the known underlying neuropathology in patients with NHD. Brain SPECT is useful for demonstrating the pathophysiologic brain region in patients with NHD.
ISSN:	0914-7187 1864-6433
DOI:	10.1007/BF02984623