Salivary osteocalcin levels are decreased in smoker chronic periodontitis patients

Oral Diseases (2011) 17, 200–205 Objectives: This study was planned to investigate whether smoker chronic periodontitis patients exhibit different salivary concentrations of C‐telopeptide pyridinoline cross‐links of type I collagen (ICTP) and osteocalcin (OC) compared to the non‐smoker counterparts. Methods: Whole saliva samples, full‐mouth clinical periodontal recordings were obtained from 33 otherwise healthy chronic periodontitis patients and 36 systemically, periodontally healthy control subjects. Chronic periodontitis patients and healthy control subjects were divided into smoker and non‐smoker groups according to their self reports. Salivary ICTP, OC levels were determined by Enzyme‐linked Immunoassays. Results: Healthy control groups exhibited significantly lower values in all clinical periodontal measurements (P 0.05). Chronic periodontitis patients exhibited significantly higher salivary OC levels than healthy controls (P